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Updated: May 14, 2026
Stimulated Single Fiber Electromyography (SFEMG) for Assessing Neuromuscular Junction Transmission in Rodent Models
Published on: March 8, 2024
[Electromyography (EMG) and neurography in patients with severe neuromuscular diseases]
Sissel Løseth1, Torberg Torbergsen
1Nevrologisk- og nevrofysiologisk avdeling, Universitetssykehuset Nord-Norge, Norway. sissel.loseth@unn.no
Background:
Many neuromuscular diseases are potentially severe, and EMG and neurography are methods used in the assessment of these conditions.
Method:
The article is based on the authors' knowledge and experience, with special emphasis on the use of these methods in the assessment of severe diseases affecting striated muscle and peripheral nerves. A PubMed search was performed with the cut-off fifteen years back in time, and in addition a discretionary selection was made of articles known to the authors.
Results:
EMG is the most valuable method for assessing myopathy, and neurography provides most information about neuropathy, but the methods are complementary. These examinations are the most sensitive for diagnosing some conditions (for example myasthaenia) A high level of expertise is necessary for diagnosing these conditions.
Interpretation:
EMG and neurography are important and often necessary means of assessing patients with severe neuromuscular disease.
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