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Interleukin-10 involvement in exposure to low dose of benzene
Giovanna Spatari1, Salvatore Saitta2, Concetto Giorgianni1
1Department of Social and Environmental Medicine, University of Messina, Messina, Italy.
Objective:
To establish if serum levels of interleukin-10 (IL-10) in subjects exposed to benzene are connected with age, working years, and employment age.
Methods:
We evaluated serum levels of IL-10 in 51 employees working in oil refinery (group A) and in 16 office workers who resided in the same area (group B).
Results:
There was no statistically significant difference between serum concentrations of IL-10 in groups A and B. There was a statistically significant dependent relationship in group A between age, working years, and serum concentration of IL-10. There was a statistically significant and positive dependent relationship in group A between serum concentration of IL-10 and employment age.
Conclusions:
The role played by IL-10 in benzene immune suppression may be relevant and attention should be directed toward assessment of age, working years, and employment age in benzene-exposed populations.
