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Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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Magnetic Resonance Imaging Quantification of Pulmonary Perfusion using Calibrated Arterial Spin Labeling
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Pulmonary perfusion MRI using interleaved variable density sampling and HighlY constrained cartesian reconstruction

Kang Wang1, Mark L Schiebler, Christopher J Francois

  • 1Global Applied Science Laboratory, GE Healthcare, Madison, WI 53705, USA. kang.wang@ge.com

Journal of Magnetic Resonance Imaging : JMRI
|January 26, 2013
PubMed
Summary
This summary is machine-generated.

This study shows that ultrafast, high-resolution whole chest MRI for pulmonary perfusion is feasible in humans. This non-cardiac gated technique offers excellent image quality with minimal artifacts, advancing lung imaging capabilities.

Keywords:
DCE MRIHYCRHYPRIVDconstrained reconstructionpulmonary perfusion

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Area of Science:

  • Medical Imaging
  • Pulmonary Medicine
  • Magnetic Resonance Imaging

Background:

  • Pulmonary perfusion imaging is crucial for diagnosing lung diseases.
  • Traditional MRI methods for lung imaging are limited by long scan times and cardiac gating requirements.
  • Ultrafast, high-resolution MRI techniques are needed to overcome these limitations.

Purpose of the Study:

  • To assess the feasibility of single breathhold, non-cardiac gated, ultrafast, high spatial-temporal resolution whole chest MRI for pulmonary perfusion in humans.
  • To evaluate the image quality and artifact levels of this novel imaging technique.

Main Methods:

  • Eight subjects (seven healthy, one with sarcoidosis) underwent whole chest MRI on a 3 Tesla scanner.
  • A 32-channel phased-array coil was used for data acquisition.
  • Radiologists independently scored gravitational effects, parenchymal enhancement, and artifacts.

Main Results:

  • The MRI pulmonary perfusion imaging was successfully performed by technologists without additional training.
  • Mean parenchymal signal was rated as very good (0.78 ± 0.13).
  • Mean motion artifact levels were low (0.13 ± 0.08).

Conclusions:

  • Single breathhold, ultrafast, high spatial-temporal resolution whole chest MR pulmonary perfusion imaging is feasible in humans.
  • The technique provides high image quality with minimal artifacts.
  • This method represents a promising advancement in non-invasive lung imaging.