Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neuropathic Deformities of the Lesser Toes.

Clinics in podiatric medicine and surgery·2026
Same author

NucVerse3D: generalizable 3D nuclear instance segmentation across heterogeneous microscopy modalities.

Scientific reports·2026
Same author

Biomechanical comparison in a cadaveric flatfoot model between different calcaneal osteotomies with and without transfer from the peroneus brevis to the longus.

Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons·2025
Same author

Disparity in access to orthopedic surgery between public and private healthcare insurance: a nationwide population-based study.

BMC musculoskeletal disorders·2025
Same author

Biomechanical Evaluation of Different Fixation Methods for Percutaneous Extracapsular Transverse Cervical Metatarsal Osteotomy in a Hallux Valgus Sawbone Model.

Foot & ankle orthopaedics·2024
Same author

Neuropathic Deformities of the Lesser Toes.

Foot and ankle clinics·2024

Related Experiment Video

Updated: May 14, 2026

Human Dupuytren's Ex Vivo Culture for the Study of Myofibroblasts and Extracellular Matrix Interactions
08:59

Human Dupuytren's Ex Vivo Culture for the Study of Myofibroblasts and Extracellular Matrix Interactions

Published on: April 18, 2015

[Dupuytren disease].

Pablo Wagner1, Javier A Román, Jorge Vergara

  • 1Departamento de Ortopedia y Traumatología, Pontificia Universidad Católica de Chile, Chile. pwagnerh1@gmail.com

Revista Medica De Chile
|January 29, 2013
PubMed
Summary

Dupuytren disease (DD) involves fibromatosis of the palm and fingers, leading to contractures that impair hand function. While its exact cause is unknown, genetics and other health conditions may play a role.

Area of Science:

  • Connective tissue disorders
  • Fibromatosis
  • Hand contractures

Context:

  • Dupuytren disease (DD) affects palmar and digital fascia, causing nodules/flanges and flexion contractures.
  • Primarily impacts the little and ring fingers, significantly reducing hand function and quality of life.
  • Associated with trauma, diabetes, alcoholism, dyslipidemia, epilepsy, and AIDS, but etiology remains unclear.

Purpose:

  • To provide a comprehensive overview of Dupuytren disease (DD).
  • To discuss the clinical presentation, potential contributing factors, and diagnostic approaches.
  • To outline current treatment strategies for DD.

Summary:

  • DD is characterized by fibromatosis leading to finger flexion contractures, impacting hand function.

More Related Videos

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
05:18

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

Related Experiment Videos

Last Updated: May 14, 2026

Human Dupuytren's Ex Vivo Culture for the Study of Myofibroblasts and Extracellular Matrix Interactions
08:59

Human Dupuytren's Ex Vivo Culture for the Study of Myofibroblasts and Extracellular Matrix Interactions

Published on: April 18, 2015

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
05:18

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

  • Etiology is multifactorial, including potential genetic links (autosomal dominant inheritance) and associations with various health conditions.
  • Diagnosis is clinical; treatment varies from observation to collagenase injections or surgery.

    • Impact:

    • Highlights the functional limitations and reduced quality of life associated with DD.
    • Emphasizes the complex and not fully understood origins of the disease.
    • Informs about the spectrum of management options available for patients with DD.