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Updated: May 14, 2026

Identification of Post-translational Modifications of Plant Protein Complexes
Published on: February 22, 2014
Palmitoylation, pathogens and their host
Mathieu Blanc1, Sanja Blaskovic, F Gisou van der Goot
1Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), Station 19, CH-1015 Lausanne, Switzerland. mathieu.blanc@epfl.ch
Abstract:
S-Palmitoylation, the only reversible post-translational lipid modification, confers unique biochemical and functional properties to proteins. Although it has long been known that viral proteins are palmitoylated, recent studies reveal that this modification plays a critical role for pathogens of all kinds and at multiple steps of their life cycle. The present review examines the involvement of S-palmitoylation in infection by viruses, bacteria and parasites and illustrates how pathogens have evolved to manipulate the host palmitoylation machinery.
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