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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Related Experiment Video

Updated: May 14, 2026

Doppler Optical Coherence Tomography of Retinal Circulation
10:46

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Published on: September 18, 2012

Dynamic gonioscopy using optical coherence tomography.

Frederic Matonti1, Elodie Chazalon, Elodie Trichet

  • 1Ophthalmology Department, Aix-Marseille University, Hôpital Nord, Institut de Neurosciences de la Timone, Aix-Marseille University, Marseille, France. frederic.matonti@ap-hm.fr

Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye
|January 30, 2013
PubMed
Summary

Anterior segment optical coherence tomography (AS-OCT) effectively assesses dynamic anterior chamber angle changes with corneal indentation. This method aids in diagnosing narrow angles, especially when gonioscopy is challenging.

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Anatomical Studies

Background:

  • Anterior segment optical coherence tomography (AS-OCT) is a non-invasive imaging technique.
  • Assessing dynamic changes in the anterior chamber angle is crucial for diagnosing glaucoma and other conditions.
  • Traditional gonioscopy can be challenging in certain patient populations.

Observation:

  • A prospective observational study utilized AS-OCT to image 21 eyes.
  • Corneal indentation was applied centrally, followed by a repeat AS-OCT scan.
  • The reopening of the anterior chamber angle and its measurements were evaluated post-indentation.

Findings:

  • AS-OCT provided accurate indirect signs for diagnosing plateau iris, confirmed by ultrabiomicroscopy.
  • Corneal indentation resulted in a significant increase in measured anterior chamber angle widths.
  • The technique demonstrated efficacy in visualizing dynamic angle changes.

Implications:

  • AS-OCT with corneal indentation offers a convenient and rapid method for assessing anterior chamber configuration.
  • This approach can assist in the routine clinical evaluation and management of patients with narrow or closed angles.
  • It provides a valuable alternative or adjunct to gonioscopy, particularly when interpretation is difficult.