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Intravitreal Gentamicin-Induced Macular Infarction: SD-OCT Features.
Summary
This case highlights spectral-domain optical coherence tomography (SD-OCT) findings of macular infarction after intravitreal gentamicin injection, showing inner retinal damage with a preserved outer retina.
Area of Science:
- Ophthalmology
- Medical Imaging
Background:
- Endophthalmitis can occur post-phacoemulsification surgery.
- Intravitreal antibiotics are standard treatment for endophthalmitis.
Purpose of the Study:
- To describe spectral-domain optical coherence tomography (SD-OCT) findings in a patient with macular infarction secondary to intravitreal gentamicin treatment for endophthalmitis.
Main Methods:
- Case report of a 75-year-old woman with post-phacoemulsification endophthalmitis.
- Treatment included intravitreal vancomycin, ceftazidime, and gentamicin.
- Spectral-domain optical coherence tomography (SD-OCT) was used to evaluate macular changes.
Main Results:
- Patient experienced persistent visual loss and macular infarction despite treatment.
- SD-OCT revealed diffuse retinal thinning, absent foveal depression, and inner retinal changes.
- Outer retina, including the inner segment/outer segment junction, remained intact.
Conclusions:
- This case illustrates characteristic SD-OCT features of inner macular infarction following intravitreal gentamicin.
- SD-OCT can differentiate inner retinal damage from outer retinal integrity in such cases.
