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Neuroplasticity01:01

Neuroplasticity

Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
Functional Brain Systems: Reticular Formation01:13

Functional Brain Systems: Reticular Formation

The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...

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Related Experiment Video

Updated: May 14, 2026

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
10:43

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

Published on: July 1, 2014

The human functional brain network demonstrates structural and dynamical resilience to targeted attack.

Karen E Joyce1, Satoru Hayasaka, Paul J Laurienti

  • 1School of Biomedical Engineering and Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America. kajoyce@wakehealth.edu

Plos Computational Biology
|January 30, 2013
PubMed
Summary

The human brain network shows remarkable resilience to damage, even when highly connected regions are removed. This study confirms the brain

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Related Experiment Videos

Last Updated: May 14, 2026

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
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Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

Published on: July 1, 2014

Modeling the Functional Network for Spatial Navigation in the Human Brain
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Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

Area of Science:

  • Neuroscience
  • Network Science
  • Computational Biology

Background:

  • Network science offers quantitative insights into complex brain interactions.
  • Previous research indicated brain networks are resilient to damage, but the impact on dynamics after removing critical nodes remains unclear.

Purpose of the Study:

  • To investigate the resilience of the human functional brain network.
  • To evaluate the impact of removing key nodes on network structure and dynamics.

Main Methods:

  • Conducted network attack experiments on voxel-wise and region-of-interest (ROI) functional brain networks.
  • Utilized functional brain networks from 5 healthy volunteers.
  • Assessed node importance using various criteria to simulate targeted attacks.

Main Results:

  • The functional human brain network demonstrates high resilience to targeted attacks.
  • Network structure and dynamics remain robust even after the removal of important nodes.

Conclusions:

  • The human brain network exhibits significant resilience, maintaining structural and dynamic integrity against targeted disruptions.
  • Findings support the robustness of brain networks in the face of node removal.