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Published on: April 9, 2021
Synthesis of biotinylated c-di-gmp and c-di-amp using click conjugation
Barbara L Gaffney1, Nicholas D Stebbins, Roger A Jones
1Department of Chemistry and Chemical Biology Rutgers, The State University of New Jersey, Piscataway, New Jersey, USA.
Nucleosides, Nucleotides & Nucleic Acids
|January 31, 2013
Abstract:
The biotinylated c-di-GMP and c-di-AMP conjugates 10a/b were synthesized by a straightforward set of procedures from standard, commercially available phosphoramidites. Their availability should allow isolation and characterization of new protein and RNA receptors for these key bacterial signaling molecules.
