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Perinatal and early postnatal factors underlying developmental delay and disabilities
1Department of Neonatology, Hebrew University Hadassah Medical School, Jerusalem, Israel. zivanit@hadassah.org.il
Developmental Disabilities Research Reviews
|January 31, 2013
Summary
Perinatal events and maternal health can impact infant development, potentially leading to developmental delays. This review examines risk factors and neuroprotective strategies for predicting long-term neurological outcomes.
Area of Science:
- Neonatology
- Developmental Pediatrics
- Neuroscience
Background:
- Developmental delays in infants can stem from perinatal events and maternal health factors.
- Complicated deliveries, prematurity, low birth weight, and intrauterine insults increase the risk of perinatal stress.
- Understanding these factors is crucial for neonatal adaptation and long-term development.
Purpose of the Study:
- To review the literature on perinatal and early postnatal factors associated with developmental delay and disabilities.
- To examine studies on neuroprotective therapies.
- To evaluate methods for predicting long-term neurologic outcomes.
Main Methods:
- Literature review of perinatal and early postnatal factors.
- Review of studies on neuroprotective interventions.
- Analysis of clinical examination, neuroimaging, and electroencephalography for outcome prediction.
Main Results:
- Perinatal events and maternal conditions significantly influence neonatal adaptation and development.
- Prematurity, low birth weight, and delivery complications are key risk factors for developmental issues.
- Clinical, neuroimaging, and electroencephalographic methods show promise in predicting neurological outcomes.
Conclusions:
- Perinatal factors play a critical role in developmental trajectories.
- Early identification and intervention are essential for managing risks associated with developmental delay.
- Neuroprotective therapies and predictive methods are vital areas for continued research.
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