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Updated: May 14, 2026

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
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Published on: November 3, 2016

Global developmental delay and mental retardation--a pediatric perspective.

Emanuel Tirosh1, Michael Jaffe

  • 1The Hannah Khoushy Child Development Center and The Bruce Rappaport Faculty of Medicine, The Technion, The Israeli Institute of Technology, Haifa, Israel. tirosh-e@b-zion.org.il

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Pediatricians are key in diagnosing global developmental delay (GDD) and mental retardation (MR). An integrated approach using clinical evaluation and multidisciplinary teams is vital for effective management and addressing family needs.

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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
19:15

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

Area of Science:

  • Pediatric Neurology
  • Developmental Pediatrics
  • Child Health

Background:

  • Global developmental delay (GDD) and mental retardation (MR) require early detection and management by pediatricians.
  • Developmental pediatricians lead the assessment, investigation, and family consultation, often within a multidisciplinary team.
  • Community health frameworks influence the models used for managing GDD and MR.

Purpose of the Study:

  • To review the literature on clinical evaluation and laboratory work-up for children with GDD/MR.
  • To emphasize a multidisciplinary team approach tailored to child and family needs.
  • To propose an integrated model for evaluation, management, and understanding the diagnosis's impact.

Main Methods:

  • Literature review focusing on clinical evaluation processes.
  • Review of laboratory investigations including neuroimaging, genetic, and metabolic tests.
  • Emphasis on a multidisciplinary team approach and family-centered care.

Main Results:

  • Significant advancements have been made in identifying etiologies of GDD/MR through various tests.
  • The diagnostic yield of investigations requires careful consideration of each test's value.
  • In-depth clinical evaluation and assessment of child/family needs are crucial for optimal knowledge utilization.

Conclusions:

  • An integrated model is proposed for developmental pediatricians, encompassing evaluation, management, and the broader consequences of diagnosis.
  • Effective management hinges on balancing diagnostic investigations with thorough clinical assessment.
  • A multidisciplinary, family-centered approach is essential for addressing the needs of children with GDD/MR.