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Preparation of Single-Cell Suspension of Mouse Thymic Epithelial Cells and Staining of Intracellular Molecules for Flow Cytometric Analysis
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Cbx4 regulates the proliferation of thymic epithelial cells and thymus function

Bo Liu1, Yuan-Feng Liu, Ya-Rui Du

  • 1Department of Immunology and Key Laboratory of Medical Immunology of Ministry of Public Health, Peking University Health Science Center, Beijing 100191, China.

Development (Cambridge, England)
|January 31, 2013
PubMed
Summary

The Polycomb protein Cbx4 is essential for thymus development. Its absence impairs thymic epithelial cell function, leading to defective T-cell development and reduced T-cell populations.

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