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Updated: May 14, 2026
09:17
Assembly of Gold Nanorods into Chiral Plasmonic Metamolecules Using DNA Origami Templates
Published on: March 5, 2019
DNA origami nanopillars as standards for three-dimensional superresolution microscopy.
Jürgen J Schmied1, Carsten Forthmann, Enrico Pibiri
1Institut für Physikalische und Theoretische Chemie, Technische Universität Braunschweig, Hans-Sommer-Strasse 10, 38106 Braunschweig, Germany.
Nano Letters
|February 1, 2013
Summary
Researchers created DNA nanopillars using DNA origami. These rigid, precisely positioned structures are ideal scaffolds for advanced applications like plasmonic devices and superresolution microscopy standards.
Area of Science:
- Nanotechnology
- Biophysics
- Materials Science
Background:
- Nanopillars are versatile nanostructures with diverse applications.
- DNA origami offers precise control over nanoscale fabrication.
Purpose of the Study:
- To develop and characterize DNA nanopillars using the DNA origami technique.
- To assess their suitability as scaffolds for advanced nanodevices.
Main Methods:
- DNA origami technique for nanopillar fabrication (220 nm height, ~14 nm diameter).
- Biotin modification for substrate immobilization.
- Site-selective dye labeling and 3D fluorescence superresolution microscopy for visualization and orientation determination.
Main Results:
- Successfully fabricated rigid DNA nanopillars with controlled dimensions.
- Achieved selective, upright immobilization on solid substrates.
- Visualized nanopillar structure and confirmed orientation using superresolution microscopy.
Conclusions:
- DNA origami nanopillars offer nanometer-precise addressability and rigidity.
- They are suitable scaffolds for assembling plasmonic devices.
- They can serve as standards for 3D superresolution microscopy.
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