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[Whipple's duodenopancreatectomy].

D Graf1, U Herzog, J P Schuppisser

  • 1Chirurgische Klinik, St. Claraspital Basel.

Schweizerische Medizinische Wochenschrift
|April 7, 1990
PubMed
Summary

This retrospective study of Whipple duodenopancreatectomy for pancreatic cancer and benign diseases found a 10% 30-day mortality. Survival rates varied by diagnosis, with benign disease offering the longest survival.

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Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Hepatobiliary Surgery

Context:

  • Retrospective analysis of 70 patients undergoing Whipple duodenopancreatectomy between 1972-1987.
  • The study evaluated indications, early, and late outcomes of the procedure.
  • Comparison of institutional results with existing literature.

Purpose:

  • To analyze the indications for Whipple duodenopancreatectomy.
  • To assess the early and late outcomes, including survival rates, for patients undergoing this procedure.
  • To compare the findings with previously published data in the medical literature.

Summary:

  • The study included 70 patients (36 male, 34 female, mean age 64). Diagnoses included pancreatic cancer (head, papilla Vateri, choledochus, other) and benign pancreatic disease.
  • 30-day mortality was 10%, exclusively in patients with carcinoma.
  • Mean survival varied: pancreatic head carcinoma (14.8 months), papilla Vateri carcinoma (32 months), distal choledochus carcinoma (20 months), other carcinoma (31 months), and benign disease (60 months).
  • Long-term survival was observed in patients with pancreatic head carcinoma, papilla Vateri carcinoma, and benign pancreatic disease.

Impact:

  • Provides insights into the long-term outcomes of Whipple duodenopancreatectomy for various pancreatic pathologies.
  • Highlights the significant impact of diagnosis on patient survival post-procedure.
  • Contributes to the understanding of surgical management and prognosis for pancreatic diseases.

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