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Updated: May 14, 2026
Fabrication of the Composite Regenerative Peripheral Nerve Interface (C-RPNI) in the Adult Rat
Published on: February 25, 2020
A Bionic Neural Link for peripheral nerve repair
Yong Ping Xu1, Shih-Cheng Yen, Kian Ann Ng
1Dept of Electrical and Computer Engineering, National University of Singapore, 4 Engineering Dr 3, Singapore. yongpingxu@nus.edu.sg
Abstract:
Peripheral nerve injuries with large gaps and long nerve regrowth paths are difficult to repair using existing surgical techniques, due to nerve degeneration and muscle atrophy. This paper proposes a Bionic Neural Link (BNL) as an alternative way for peripheral nerve repair. The concept of the BNL is described, along with the hypothetical benefits. A prototype monolithic single channel BNL has been developed, which consists of 16 neural recording channels and one stimulation channel, and is implemented in a 0.35-µm CMOS technology. The BNL has been tested in in-vivo animal experiments. Full function of the BNL chip has been demonstrated.
