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Updated: May 14, 2026

Implantation of Left Ventricular Assist Device (LVAD) in Juvenile Landrace Swine: A LVAD Implantation Model of Pediatric Heart Failure
Published on: January 16, 2026
Feasibility of using piezohydraulic pumps as motors for pediatric ventricular assist devices
John Valdovinos1, Daniel S Levi, Ryan Williams
1Biomedical Engineering Interdepartmental Program, University of California Los Angeles, Los Angeles, CA 90095, USA. johnvald@ucla.edu
Abstract:
The feasibility of using piezohydraulic pumps in drivers for pediatric ventricular assist devices is presented in this article. In this study a 0.5 kg piezohydraulic pump is incorporated into a ventricular assist device driver to drive a pulsatile pediatric 30 mL stroke ventricular assist device (VAD). The driver consists of a piezoelectric-hydraulic hybrid actuator and volume amplification section. Mechanical tests were performed on the pump and the hybrid actuator and a maximum power output of 5.4 W and 1.6 W were recorded respectively. The driver was tested running at multiple heart rates from 50-80 beats per minute (BPM) in an in-vitro bench top mock circulation to characterize the performance of the driver under a circulatory load. The maximum drive pressure output by the driver was 35 kPa. Peak flow rate from the VAD driven by the new driver was 6 L/min against a 10 kPa back pressure. Mean flow rate from the VAD outlet was 2.35 L/min for 80 BPM operation.
