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Related Concept Videos

Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

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Related Experiment Video

Updated: May 14, 2026

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test
08:10

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test

Published on: April 9, 2012

[Can an individual with a positive baseline QuantiFERON test result develop active tuberculosis?].

Lina Yi1, Takashi Yoshiyama, Masao Okumura

  • 1Fukujuji Hospital, Japan Anti-Tuberculosis Association. yi-lina@hotmail.com

Kekkaku : [Tuberculosis]
|February 2, 2013
PubMed
Summary

The QuantiFERON-TB Gold (QFT-G) test identifies latent tuberculosis infection. Individuals with a positive QFT-G test showed a low risk of developing active tuberculosis, especially if not recently infected.

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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

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Last Updated: May 14, 2026

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test
08:10

Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test

Published on: April 9, 2012

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Area of Science:

  • Infectious Diseases
  • Immunology
  • Public Health

Context:

  • Latent tuberculosis infection (LTBI) diagnosis relies on tests like QuantiFERON-TB Gold (QFT-G).
  • The risk of progressing from LTBI to active tuberculosis (TB) varies over time post-infection.
  • Understanding this risk is crucial for managing LTBI and preventing active disease.

Purpose:

  • To evaluate the risk of developing active TB in individuals with a positive QFT-G test result.
  • To assess the long-term clinical outcomes for healthcare workers diagnosed with LTBI using QFT-G.

Summary:

  • A retrospective analysis of 667 healthcare workers using the QFT-G test identified 62 positive cases.
  • Sixty-one subjects with positive QFT-G results were followed for an average of 4.7 years (286 person-years).
  • No participants developed active TB during the study period, indicating a low probability of clinical progression (0-0.0104/person-year).

Impact:

  • The findings suggest a low risk of active TB development in individuals with a positive QFT-G test, particularly if infection was not recent.
  • This supports a cautious approach to treating LTBI, recommending intervention primarily for recently infected individuals.
  • The study contributes to evidence-based guidelines for managing LTBI and preventing TB transmission.