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Related Experiment Videos

Tear buffering in contact lens wearers.

L G Carney1, T F Mauger, R M Hill

  • 1College of Optometry, Ohio State University, Columbus.

Acta Ophthalmologica
|February 1, 1990
PubMed
Summary

Contact lens wear does not significantly alter tear buffering capacity. Researchers found considerable variation between individuals, regardless of lens type or wear status, in this study on tear pH.

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Area of Science:

  • Ophthalmology
  • Physiological Optics
  • Biochemistry

Background:

  • Tear film stability and composition are crucial for ocular surface health.
  • Contact lens wear can potentially influence the ocular surface environment, including tear physiology.
  • Understanding tear buffering capacity is important for assessing ocular surface tolerance to contact lenses.

Purpose of the Study:

  • To compare the buffering capacity of tears in contact lens wearers versus non-wearers.
  • To investigate the effect of rigid and hydrogel contact lenses on tear buffering.
  • To assess inter-subject variability in tear buffering capacity.

Main Methods:

  • Tears were collected from 12 subjects (non-wearers, rigid lens wearers, hydrogel lens wearers).
  • Tear pH was measured using a micro-electrode system before and after acid-base titration.
  • Buffering capacity was assessed by comparing tear pH response to distilled water under titration.

Main Results:

  • No statistically significant difference in tear buffering capacity was found between contact lens wearers and non-wearers.
  • Significant inter-subject variability in tear buffering capacity was observed across all groups.
  • The buffering capacity of tears was generally higher than that of unbuffered distilled water.

Conclusions:

  • Contact lens wear, whether rigid or hydrogel, does not appear to significantly impact the intrinsic buffering capacity of human tears.
  • Individual physiological differences play a substantial role in tear buffering capacity.
  • Further research may explore other tear film parameters affected by contact lens wear.

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