Related Experiment Video
Updated: May 14, 2026

08:49
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Nonmelanoma skin cancer
Lauren E Dubas1, Adam Ingraffea
1Department of Dermatology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
Facial Plastic Surgery Clinics of North America
|February 2, 2013
Summary
Nonmelanoma skin cancer (NMSC) is the most common human malignancy, with rising incidence. Prompt diagnosis and management of NMSC are crucial to prevent severe illness and death.
Area of Science:
- Oncology
- Dermatology
Background:
- Nonmelanoma skin cancer (NMSC) represents the most prevalent human malignancy.
- NMSC incidence is increasing globally, despite public health efforts.
- Untreated or improperly managed NMSC can lead to substantial morbidity and mortality.
Purpose of the Study:
- To review the common types of NMSC affecting the head and neck.
- To outline current and emerging treatment modalities for NMSC.
Main Methods:
- Literature review of NMSC epidemiology, pathology, and treatment.
- Synthesis of information on surgical and non-surgical therapeutic options.
Main Results:
- Common head and neck NMSC types include basal cell carcinoma and squamous cell carcinoma.
- Surgical interventions like Mohs micrographic surgery are primary treatments.
- Radiation, topical treatments, photodynamic therapy, and systemic drugs offer alternative or adjuvant options.
Conclusions:
- Effective management of NMSC requires a comprehensive approach.
- Multidisciplinary treatment strategies are essential for optimal patient outcomes in NMSC care.
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