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Updated: May 14, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Posterior cranial fossa meningiomas.

Vijayakumar Javalkar¹, Anirban Deep Banerjee, Anil Nanda

¹Department of Neurosurgery, Louisiana State University Health Sciences Center, Shreveport, Louisiana.

Journal of Neurological Surgery. Part B, Skull Base

|February 2, 2013

Summary

This study on posterior fossa meningiomas found that while gross total resection is ideal, balancing extent of resection with functional outcomes is crucial due to proximity to critical structures. Recurrence rates were 18.7%.

Keywords:

meningiomas posterior fossa skull base

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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

Area of Science:

Neurosurgery
Oncology

Background:

Posterior cranial fossa meningiomas represent a significant subset of intracranial tumors.
Surgical management aims for maximal safe resection while preserving neurological function.

Purpose of the Study:

To evaluate surgical outcomes, complication rates, and recurrence patterns of posterior cranial fossa meningiomas.
To analyze the feasibility of gross total resection versus subtotal resection with adjuvant therapy.

Main Methods:

Retrospective review of 64 surgical cases of posterior cranial fossa meningiomas.
Analysis of surgical approaches, complications, extent of resection, and long-term follow-up data.

Main Results:

Headache was the most frequent symptom; retrosigmoid approach was common.
Cranial nerve complications occurred in 28%, with 11% experiencing facial nerve weakness.
Gross total resection was achieved in 58%; 25% received Gamma Knife radiosurgery for residual tumors.
Recurrence or progression was observed in 18.7% of cases, with a 3.1% operative mortality.

Conclusions:

Achieving gross total resection is challenging in posterior fossa meningiomas due to critical structure proximity.
A balance between maximal resection and favorable functional outcomes (93% GOS 4-5) is essential.
Adjuvant radiosurgery is a viable option for residual tumors.