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Updated: May 14, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Denervation change of tensor veli palati in obstructive sleep apnea hypopnea syndrome]
Yifang Yang1, Xian Zhang, Xianming Chen
1Department of Otolaryngology-Head and Neck Surgery, Fuzhou General Hospital of PLA, Nanjing Military Region, Fuzhou, 350025, China.
Objective:
To explore the denervation change of Tensor Veli Palati in patients with OSAHS by determine the mRNA and protein expression of NCAM.
Method:
The OSAHS group was consisted of 30 OSAHS patients and the normal control group was consisted of 10 chronic tonsillitis patients without OSAHS. Real-time quantitative RT-PCR and Western blot methods were used to determine the NCAM expression in specimens.
Result:
(1) The mRNA and protein expression level of NCAM in the OSAHS group increased significantly compared with that in control group (P < 0.05). (2) There was positive correlation between AHI and the protein expression level of NCAM in the OSAHS group (r = 0.803, P < 0.01).
Conclusion:
These results indicate that the denervation change of tensor veli palati appear in OSAHS patients, and the severity of OSAHS are relevant with the degree of denervation.
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