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Related Concept Videos

Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Experiment Video

Updated: May 14, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
08:49

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Published on: May 18, 2018

Multiple primary melanomas: do they look the same?

E Moscarella1, H Rabinovitz, S Puig

  • 1Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.

The British Journal of Dermatology
|February 5, 2013
PubMed
Summary
This summary is machine-generated.

Multiple primary melanomas (MPMs) have nearly equal chances of appearing dermoscopically similar or different within an individual. However, elderly patients with sun-damaged skin may develop multiple, similar, thin melanomas.

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Area of Science:

  • Dermatology
  • Oncology
  • Dermoscopy

Background:

  • Multiple primary melanomas (MPMs) are increasingly studied for their epidemiological, clinical, and genetic aspects.
  • Previous research has primarily focused on these characteristics, with limited case reports comparing dermoscopic features within individuals.

Purpose of the Study:

  • To compare dermoscopic features of multiple primary melanomas (MPMs) within individual patients.
  • To identify clinical characteristics associated with similar or dissimilar dermoscopic appearances of MPMs.

Main Methods:

  • Dermoscopic images of melanomas from patients diagnosed with multiple primary melanomas (MPMs) were collected.
  • Data were gathered from three international skin-lesion clinics in the USA, Italy, and Spain.

Main Results:

  • 53% of patients with MPMs exhibited dermoscopically similar melanomas, while 47% had dissimilar ones.
  • Similar melanomas were associated with similar thickness (63%), synchronous lesions (65%), and sun-damaged skin (69%).
  • Dermoscopically different melanomas were more frequent in patients with a family history of melanoma (67%).

Conclusions:

  • Multiple primary melanomas (MPMs) have a near 50/50 chance of being dermoscopically similar or different within a single patient.
  • Elderly patients with sun-damaged skin may present with multiple, similar, thin melanomas, often showing pigment-network and regression structures.