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[Visual neurorehabilitation of patients with cerebral damage using botulinum toxin]
Silvia Moguel-Ancheita1, Adriana Valdés-Barrena, Fátima Guadalupe Padilla-Sánchez
1Servicio de Oftalmología, Departamento de Estrabismo. Centro Médico Nacional 20 de Noviembre, ISSSTE, México, D.F., Mexico. smoguel@prodigy.net.mx
Background:
The neurorehabilitation of the patient with cerebral damage implies the reestablishment of the visual functions. Botulinum toxin can be considerate as a less invasive alternative for treatment.
Objective:
to demonstrate the answer to the treatment using botulinum toxin of the visual motor alterations in patients with cerebral damage.
Methods:
Descriptive study of patients with visual alterations associated to cerebral damage. The visual treatment included three areas: sensorial, refracting and motor under quimiodenervation with botulinum toxin, of May 2009 to May 2010.
Results:
48 patients were studied, age 22,4 years ± 23. The strabismus were: esotropia 52%, exotropia 39,5%, vertical 8%, nystagmus 4%. 50% of the patients had psychomotor delay. Some of the most important causes of cerebral damage were: Down syndrome, epilepsy, tumor, hydrocephalus, neuroinfection, infantile cerebral paralysis, multiple sclerosis, metabolic syndrome, cranial trauma, congenital cardiopathy, ventricular hemorrhage, cerebrovascular stroke. The dose of botulinum toxin was 8,1 UI ± 3. We registered good results in 56.5%, regular 23,9% and bad 19,5%. The global percentage of rehabilitation was 69% of correction with a r of Pearson of 0,5.
Discussion:
Patients with cerebral damage have diverse types of visuomotor alterations, strabismus and nystagmus.Use of botulinum toxin as a paralytic muscle agent is a good alternative in these cases.
Conclusion:
The botulinum toxin is an effective option for the visual rehabilitation in patients with cerebral damage and prevents the progression of more cerebral changes secondary to strabismus.