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Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Published on: March 1, 2024

Haematological parameters and recurrent aphthous stomatitis.

Nabiha Farasat Khan¹, Mohammad Saeed, Saima Chaudhary

¹Department of Oral Pathology, Dental Section, Bolan Medical College, Quetta. nabihasaeed@hotmail.com

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

|February 5, 2013

Summary

Recurrent aphthous stomatitis (RAS) is linked to deficiencies in key nutrients like serum vitamin B12 and red blood cells (RBC) folate. These deficiencies were significantly more common in patients with RAS, highlighting a crucial relationship.

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Area of Science:

Oral health
Nutritional science
Hematology

Background:

Recurrent aphthous stomatitis (RAS) is a common oral condition.
The role of nutritional deficiencies in RAS etiology is not fully understood.

Purpose of the Study:

To investigate the association between recurrent aphthous stomatitis (RAS) and deficiencies in hemoglobin, hematocrit, serum vitamin B12, serum ferritin, and red blood cells (RBC) folate levels.

Main Methods:

An analytical cross-sectional study was conducted with 60 RAS patients and 60 controls.
Blood samples were analyzed for serum B12, RBC folate, serum ferritin, hemoglobin, and hematocrit.
Statistical analysis compared the proportion of subjects with lower values between groups.

Main Results:

Significantly lower levels of serum ferritin, hematocrit, RBC folate, and serum B12 were observed in the RAS group.
A combined deficiency state involving hemoglobin, serum ferritin, hematocrit, RBC folate, and serum B12 was identified in 13% of RAS patients.

Conclusions:

There is a high frequency of hematinic deficiencies in patients with recurrent aphthous stomatitis.
Serum vitamin B12 and RBC folate deficiencies are significantly associated with RAS.