Related Experiment Video
Updated: May 14, 2026

Direct Reprogramming of Mouse Fibroblasts into Melanocytes
Published on: August 27, 2021
[Vitiligo as an aesthetic problem. Noninvasive therapeutic methods in vitiligo]
Magdalena Popko1, Anna Kacalak-Rzepka, Stanisława Bielecka-Grzela
1Katedra i Klinika Chorób Skórnych i Wenerycznych Pomorskiego Uniwersytetu Medycznego w Szczecinie, al. Powstańców Wlkp. 72, 70-111 Szczecin.
Abstract:
Vitiligo is an idiopathic chronic skin disease that is notable for depigmented macules forming by destruction of melanocytes mediated by cells of the immune system. Vitiligo occurs in 1-2% of the population irrespective of race and without predilection to gender or age. The dynamics and extent of the disease vary widely, ranging from stable cases with isolated minor foci to states showing rapid progression and occupying large areas of the skin. For many patients, the disease represents a serious cosmetic defect which limits their activities in various spheres of life. There are many noninvasive methods of treatment but none of them offers a guarantee of complete therapeutic success. PUVA- and UVB-therapy are recognized as the most effective and most commonly used methods. The management of vitiligo should also include education, cosmetic correction options, and psychotherapy in some cases.
Related Concept Videos
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Acne Infection
