Related Experiment Video
Updated: May 14, 2026

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
Published on: July 12, 2018
[Current concepts of perforated sigmoid diverticulitis]
Alexandre Descloux1, Markus Doß, Andreas Keerl
1Klinik für Allgemein-, Viszeral- und Gefässchirurgie, Kantonsspital Baden.
Perforated sigmoid diverticulitis is dangerous. Treatment depends on whether the perforation is covered or free, prioritizing bowel resection to prevent sepsis. Advanced cases may need Hartmann
Area of Science:
- Gastroenterology
- Surgical Oncology
- Abdominal Surgery
Background:
- Perforated sigmoid diverticulitis remains a life-threatening condition despite advances in therapy.
- Distinguishing between covered and free perforations is crucial for appropriate management.
- Abdominal sepsis is a primary concern, necessitating prompt intervention.
Purpose of the Study:
- To outline diagnostic and therapeutic strategies for perforated sigmoid diverticulitis.
- To differentiate management approaches for covered versus free perforations.
- To discuss the role of individual risk profiles and surgical experience in treatment decisions.
Main Methods:
- Review of current therapeutic options for perforated sigmoid diverticulitis.
- Emphasis on surgical resection as the primary goal for free perforations.
- Discussion of conservative management and interventional drainage for covered perforations.
Main Results:
- Excision of the inflamed bowel segment is key to preventing abdominal sepsis.
- Primary anastomosis is preferred for free perforations when feasible.
- Hartmann procedure may be necessary in advanced or complicated cases.
- Individualized treatment decisions are based on risk profiles and peritonitis severity.
Conclusions:
- Management of perforated sigmoid diverticulitis requires careful consideration of perforation type and patient factors.
- Surgical resection remains the cornerstone of treatment for free perforations.
- Emerging techniques like laparoscopic lavage require further investigation and validation.
Related Concept Videos
Diverticular Disease of the Colon
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Appendicitis
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease I: Introduction

