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Oxybutynin treatment for hyperhidrosis: a comparative analysis between genders
Nelson Wolosker1, Mariana Krutman, Taiz Pereira Donozo Almeida Campdell
1Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Einstein (Sao Paulo, Brazil)
|February 7, 2013
Summary
Low-dose oxybutynin effectively treats palmar and axillary hyperhidrosis in both men and women. This study found similar improvements in quality of life and symptom severity across genders.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Hyperhidrosis, a condition causing excessive sweating, affects both palmar and axillary regions.
- Current treatments for hyperhidrosis have varying efficacy and side effect profiles.
Purpose of the Study:
- To evaluate the effectiveness of low-dose oxybutynin for treating palmar and axillary hyperhidrosis.
- To compare treatment outcomes between male and female patients.
Main Methods:
- Retrospective analysis of 395 women and 170 men with palmar and axillary hyperhidrosis.
- Patients were treated with low doses of oxybutynin.
Main Results:
- 70% of patients experienced partial or significant improvement in hyperhidrosis.
- 40% of female patients reported "great" improvement; overall quality of life improved for approximately 70% of all patients.
- 30% of patients reported no change in their condition.
Conclusions:
- Oxybutynin treatment for hyperhidrosis shows similar efficacy in both genders.
- Gender does not significantly impact the results of oxybutynin therapy for hyperhidrosis.
- Significant improvements in quality of life were observed in both male and female patients.
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