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Updated: May 14, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
06:01

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Hemorrhagic cardioembolic stroke secondary to a left ventricular thrombus: a therapeutic dilemma

Khalil Al-Farsi1, Aftab A Siddiqui, Yasser W Sharef

  • 1Consultant, Department of Hematology, Sultan Qaboos University Hospital, P.O. Box 35, AlKhodh 123, Muscat, Sultanate of Oman.

Oman Medical Journal
|February 7, 2013
PubMed

Insights

Cardiogenic embolism from a left ventricular thrombus caused multiple brain infarctions. A multidisciplinary approach with anticoagulation and monitoring improved patient outcomes.

Area of Science:

  • Cardiology
  • Neurology
  • Vascular Medicine

Background:

  • Cardiogenic embolism is a primary cause of ischemic stroke, contributing significantly to patient morbidity and mortality.
  • Despite advancements, diagnosing and managing complex stroke cases, such as those arising from cardiac thrombi, remains challenging.

Observation:

  • A 50-year-old male presented with multi-territory cerebral infarctions.
  • The cause was identified as a mobile left ventricular thrombus.
  • Hemorrhagic transformation was noted at presentation.

Findings:

  • Gradual anticoagulation therapy was initiated.
  • A multidisciplinary team approach was employed, involving close clinical monitoring.
  • Regular echocardiographic and neuroimaging studies guided management.

Implications:

  • This case highlights the importance of a comprehensive, team-based strategy for managing challenging cardiogenic stroke presentations.
  • Effective management can lead to improved therapeutic outcomes even in complex scenarios.
  • Early and regular diagnostic imaging is crucial for monitoring treatment response and preventing complications.

Keywords:
CardioembolismEchocardiographyHemorrhagic transformationMobile thrombusMultidisciplinary approachStroke

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