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Angiographic control and percutaneous treatment of myocardial ischemia immediately after CABG
Janko Szavits-Nossan1, Hrvoje Stipić, Igor Sesto
1"J. J. Strossmayer" University, "Magdalena" Clinic for Cardiovascular Diseases, Department of Cardiology, Krapinske Toplice, Croatia. janko.szavits-nossan@magdalena.hr
Insights
Graft dysfunction is a common cause of perioperative myocardial ischemia after coronary artery bypass grafting (CABG). Angiography-guided percutaneous intervention can reduce the high mortality rate in these patients.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Medical Imaging
Background:
- Perioperative myocardial ischemia is a rare but serious complication following coronary artery bypass grafting (CABG).
- Existing treatments for this condition have shown limited success.
- A treatment strategy guided by coronary angiography findings may improve outcomes.
Purpose of the Study:
- To analyze the causes of perioperative myocardial ischemia after CABG.
- To evaluate the effectiveness of an angiography-based treatment strategy, including percutaneous intervention.
Main Methods:
- A prospective longitudinal study involving 55 consecutive patients who underwent early coronary angiography for perioperative myocardial ischemia.
- Analysis of causes of ischemia, including graft-related issues, thrombosis, and incomplete revascularization.
- Treatment decisions based on coronary angiography findings: percutaneous intervention, additional grafting, or no intervention.
Main Results:
- Incorrect graft anastomosis was the most frequent cause of ischemia (49%).
- Percutaneous intervention was performed in 30 patients with a 97% primary success rate.
- Overall in-hospital mortality was 30%.
Conclusions:
- Graft dysfunction, particularly incorrect anastomosis, is a primary cause of perioperative myocardial ischemia post-CABG.
- Percutaneous intervention guided by coronary angiography can potentially reduce the high mortality rate associated with this complication.
Abstract:
Perioperative myocardial ischemia is rare but serious complication of CABG. Graft dysfunction, coronary artery thrombosis and incomplete revascularization are main causes. Pharmacological treatment, intra aortic counter pulsation and immediate additional grafting have limited results. Treatment strategy based on coronary angiography findings could lessen the burden of high mortality rate in these patients. The purpose of this study was to analyze the causes of perioperative ischemia and angiography based treatment strategy including percutaneous intervention. We enrolled all 55 consecutive patients that went early coronary angiography for perioperative myocardial ischemia in a prospective longitudinal study. Incorrect graft anastomosis, graft spasm, displacement and dissection were found in 49%, 7%, 5% and 4% of patients, respectively. Acute coronary artery thrombotic occlusion was found in 5% of patients and ischemia due to incomplete revascularization in 6% of patients. In 22% of patients no cause of myocardial ischemia could be detected. There were no complications of coronary angiography. Based on coronary angiography findings percutaneous intervention was performed in 30 patients, additional grafting in 8 patients and no action was taken in 17 patients. Percutaneous intervention with stenting was performed on coronary arteries (78%) and graft anastomosis (22%) with primary success 97%. One anastomosis rupture with treatable tamponade and one lethal stent thrombosis were complications of percutaneous treatment. Overall in hospital mortality was 30%. We concluded that graft dysfunction is usual cause of myocardial ischemia due to incorrect anastomosis and that percutaneous intervention on bypass graft or coronary artery can lessen high mortality rate in these patients.
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