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Published on: December 11, 2017
Atrial fibrillation, atrioventricular blocks and bundle branch blocks in hemodialysis patients
Ante Mandić1, Monika Tomić, Bozo Petrov
1Health Center Siroki Brijeg, Siroki Brijeg, Bosnia and Herzegovina. ante.mandic@live.com
Insights
This study found a high prevalence of atrial fibrillation and bundle branch blocks in hemodialysis patients, exceeding general population rates. Older age and higher uric acid levels were linked to atrial fibrillation.
Area of Science:
- Nephrology
- Cardiology
- Clinical Electrophysiology
Background:
- Atrial fibrillation is common in dialysis patients, but other conduction disturbances are less studied.
- There is insufficient data on the prevalence of atrioventricular and intraventricular conduction disturbances in hemodialysis patients.
Purpose of the Study:
- To determine the prevalence of atrial fibrillation, atrioventricular blocks, and bundle branch blocks in hemodialysis patients.
- To identify clinical risk factors associated with these arrhythmias in this population.
Main Methods:
- Electrocardiogram (ECG) was used to diagnose arrhythmias in 140 long-term hemodialysis patients.
- Patients were grouped based on the presence or absence of atrial fibrillation/bundle branch blocks for variable comparison.
Main Results:
- Atrial fibrillation was present in 7.9% of patients, associated with older age and higher uric acid.
- Bundle branch blocks (various types) were found in 17.1% of patients.
- First-degree atrioventricular block was present in 2.9%; higher-degree AV blocks were absent.
Conclusions:
- The prevalence of atrial fibrillation and bundle branch blocks is notably high in hemodialysis patients compared to the general population.
- Older age and elevated uric acid are significant risk factors for atrial fibrillation in this cohort.
- Further investigation into cardiac conduction disturbances in dialysis patients is warranted.
Abstract:
Atrial fibrillation is one of the most frequent arrhythmias diagnosed in clinical practice and it is also relatively common in dialysis patients. Atrioventricular and intraventricular conduction disturbances are less investigated in hemodialysis patients and data about their prevalence are insufficient. The objective of this study was to determine the prevalence of atrial fibrillation, atrioventricular blocks and bundle branch blocks in hemodialysis patients and to analyze different clinical risk factors. The study included 140 patients on long-term hemodialysis treatment. The presence of atrial fibrillation, atrioventricular blocks and bundle branch blocks was determined by electrocardiogram. Patients were divided into groups depending on the presence or absence of atrial fibrillation/bundle branch blocks and investigated variables were compared. Atrial fibrillation was present in 11 (7.9%) of the 140 patients. In multivariate analysis, age and higher concentration of uric acid were associated with atrial fibrillation. Prevalence of first-degree atrioventricular block was 2.9% (4 patients) and second- and third-degree atrioventricular blocks were not found. Prevalence of bundle branch blocks was 17.1% (24 patients): 5% of patients had a complete right bundle branch block, 6.4% had an incomplete right bundle branch block, 3.6% had a complete left bundle branch block and 2.1% of patients had an incomplete left bundle branch block. The prevalence of atrial fibrillation and bundle branch blocks in this study was relatively high in patients on hemodialysis and greater than that observed in general population. Presence of atrial fibrillation was associated with older age and higher concentration of uric acid.
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