Imaging of neuroendocrine tumors

Neuroendocrine tumors (NETs) are a heterogeneous group of neoplasms that differ in their biological, chemical, and physical behaviors depending on the degree of differentiation and locations. Consequently, evaluation of these tumors is complex, requiring clinical history, physical examination, laboratory data, and imaging. With advances in morphologic and functional imaging techniques, we now have tools for caring of patients with these tumors at diagnosis, staging, treatment assessment, and prognosis prediction. In general, no single imaging modality can provide all the necessary information. However, well-chosen combinations of available imaging modalities based on the indications, strength and limitations of the modalities, and local expertise will provide optimal evaluation of patients with NETs.