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Pancreatic candidiasis. A case report.

A Mannell1, V Obers

  • 1Department of Surgery, School of Pathology, South African Institute for Medical Research, Johannesburg.

South African Journal of Surgery. Suid-Afrikaanse Tydskrif Vir Chirurgie
|March 1, 1990
PubMed
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A rare case of pancreatic candidiasis, a fungal infection, was found in a patient initially suspected of having pancreatic cancer. Diagnosis was confirmed post-surgery, revealing pancreatitis complicated by candidiasis.

Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Surgical Pathology

Background:

  • Pancreatic masses can mimic adenocarcinoma, necessitating thorough histopathological analysis.
  • Fungal infections like candidiasis are uncommon in the pancreas, especially without predisposing factors.

Observation:

  • A patient presented with symptoms suggestive of pancreatic cancer, including weight loss and obstructive jaundice.
  • Intra-operative cytology indicated adenocarcinoma, leading to a pancreaticoduodenectomy.
  • Histological examination of the resected specimen revealed acute-on-chronic pancreatitis with Candida albicans infection.

Findings:

  • The resected specimen showed no evidence of malignancy, contrary to initial cytologic findings.
  • The pancreatic condition was diagnosed as pancreatitis complicated by candidiasis.

Related Experiment Videos

  • This case highlights a rare association between pancreatic candidiasis and acute pancreatitis.

    • Implications:

    • Accurate differentiation between pancreatic cancer and inflammatory conditions with superimposed infection is crucial.
    • Further research is needed to understand the pathogenesis and clinical significance of pancreatic candidiasis.
    • This case underscores the importance of comprehensive histopathological evaluation in pancreatic diseases.