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Updated: May 14, 2026
10:21
Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix
Published on: June 14, 2016
[Mesenterial fibrosis--could it be desmoidi?].
Annika Auranen1, Markku Kallajoki, Maija Lavonius
1TYKS:n naistenklinikka.
Duodecim; Laaketieteellinen Aikakauskirja
|February 12, 2013
Summary
Desmoid tumors are rare fibrous growths that invade locally. Mesenteric desmoids present diagnostic challenges, but treatments like pegylated liposomal doxorubicin can maintain quality of life.
Area of Science:
- Oncology
- Surgical Pathology
- Gastroenterology
Context:
- Desmoid tumors are rare, locally invasive benign fibrous neoplasms.
- Mesenteric desmoid tumors constitute a minority of cases.
- Their misleading symptoms often lead to delayed diagnosis.
Purpose:
- To review the characteristics, diagnostic challenges, and treatment options for mesenteric desmoid tumors.
- To highlight the complexities of surgical management due to tumor location.
- To discuss alternative therapies for unresectable cases.
Summary:
- Complete surgical excision is the primary treatment, but challenging in the mesentery.
- Non-surgical options include antiestrogens, NSAIDs, and chemotherapy.
- Pegylated liposomal doxorubicin has shown promising response rates.
- Quality of life can often be preserved, even in advanced or unresectable disease.
Impact:
- Improved understanding of mesenteric desmoid tumor management.
- Guidance on therapeutic strategies for challenging tumor locations.
- Potential for better patient outcomes and quality of life preservation.
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