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Updated: May 14, 2026

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Targeted Muscle Reinnervation: Surgical Protocol for a Randomized Controlled Trial in Postamputation Pain
Published on: March 8, 2024
The traumatic lower extremity amputee: surgical challenges and advances in prosthetics
Lisa K Cannada1, Rahul Vaidya, Dana C Covey
1Department of Orthopaedic Surgery, Saint Louis University, St. Louis, MO, USA.
Abstract:
The mangled lower extremity is a challenging injury to treat. Orthopaedic surgeons treating patients with these severe injuries must have a clear understanding of contemporary advantages and disadvantages of limb salvage versus amputation. It is helpful to review the acute management of mangled extremity injuries in the civilian and military populations, to be familiar with current postoperative protocols, and to recognize recent advances in prosthetic devices.
