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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Related Experiment Video

Updated: May 14, 2026

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery
12:04

Intra-Operative Behavioral Tasks in Awake Humans Undergoing Deep Brain Stimulation Surgery

Published on: January 6, 2011

Probing and regulating dysfunctional circuits using deep brain stimulation.

Andres M Lozano1, Nir Lipsman

  • 1Division of Neurosurgery, Department of Surgery, Toronto Western Hospital, Krembil Neuroscience Center, University of Toronto, Toronto, ON M5T 2S8, Canada. lozano@uhnresearch.ca

Neuron
|February 12, 2013
PubMed
Summary
This summary is machine-generated.

Deep brain stimulation (DBS) is a powerful tool for understanding and treating neurologic and psychiatric disorders by recalibrating dysfunctional brain circuits. Research is actively exploring new applications for this neuromodulation technique.

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Controlling Parkinson's Disease With Adaptive Deep Brain Stimulation
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Last Updated: May 14, 2026

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Published on: January 6, 2011

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
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Area of Science:

  • Neurology
  • Neurosurgery
  • Neuroscience

Background:

  • Many patients remain disabled by neurologic and psychiatric disorders despite current treatments.
  • Recent advances reframe these conditions as circuit function disorders (circuitopathies).
  • Neurosurgical techniques have advanced, enabling wider use of deep brain stimulation (DBS).

Purpose of the Study:

  • To review recent advances in deep brain stimulation (DBS).
  • To discuss future directions for targeted intracranial neuromodulation.
  • To highlight DBS as a tool for studying brain circuit dysfunction.

Main Methods:

  • Review of recent advances in DBS technology and application.
  • Analysis of DBS's role in understanding circuitopathies.
  • Discussion of future research and therapeutic potential.

Main Results:

  • Deep brain stimulation (DBS) is increasingly utilized to recalibrate dysfunctional neural circuits.
  • DBS serves as a versatile tool for probing and modulating brain circuits.
  • DBS provides insights into the pathophysiology of circuit dysfunction.

Conclusions:

  • Deep brain stimulation (DBS) shows significant promise for treating a wider range of neurologic and psychiatric disorders.
  • Further research is needed to identify optimal targets and applications for intracranial neuromodulation.
  • The field is advancing towards more targeted neuromodulation strategies.