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A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments
Published on: November 9, 2017
[Guillain-Barré syndrome heralding acute query fever]
A-M Grapperon1, D Wybrecht, S Pons
1Service de neurologie, hôpital d'instruction des armées Sainte-Anne, boulevard Sainte-Anne, BP 20545, 83041 Toulon cedex 9, France.
Introduction:
Q fever is a polymorphic disease, which can induce neurological disturbances. The central nervous system is mainly involved while peripheral neuropathies are rare with less than 15 cases reported in the literature.
Case-Report:
We report here a case of acute polyradiculoneuritis associated with acute Q fever, with favorable outcome after antibiotic and intravenous immunoglobulin therapies.
Conclusion:
Serologic tests for Coxiella burnetii should be performed in case of unusual polyradiculoneuritis with fever, headache and neuro-ophthalmologic disorders, even when environmental exposure is lacking, because Q fever requires specific antibiotic treatment and serological follow-up.
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