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Consensus statement for inert gas washout measurement using multiple- and single- breath tests.
Paul D Robinson1, Philipp Latzin, Sylvia Verbanck
1Dept of Respiratory Medicine, The Children’s Hospital at Westmead, Westmead, Sydney, Australia. dr.pdrobinson@gmail.com
The European Respiratory Journal
|February 12, 2013
Summary
Inert gas washout tests offer sensitive detection of early lung damage and improved feasibility across age groups. This paper provides essential guidelines for their clinical application, addressing a lack of standardized protocols.
Area of Science:
- Pulmonary Physiology
- Respiratory Medicine
Background:
- Inert gas washout (IGW) tests, including single- and multiple-breath techniques, have been available for over 60 years.
- These tests measure ventilation distribution inhomogeneity, providing complementary data to spirometry.
- IGW tests show promise for early detection of lung damage and broader age applicability.
Purpose of the Study:
- To provide evidence-based recommendations for IGW equipment, performance, and analysis.
- To address the lack of detailed guidelines for these valuable lung function tests.
- To facilitate the integration of IGW testing into routine clinical practice.
Main Methods:
- Development of recommendations based on evidence and expert opinion from a dedicated working group.
- Focus on principles essential for understanding IGW test performance and interpretation.
- Consideration of both paediatric and adult testing environments.
Main Results:
- Detailed recommendations are provided for IGW equipment specifications, test execution, and data analysis.
- Key principles underlying IGW techniques are outlined for clarity.
- Unanswered questions and areas for future research are highlighted.
Conclusions:
- Standardized guidelines are crucial for the effective implementation of IGW tests.
- These recommendations aim to improve the consistency and reliability of IGW testing.
- Further research is needed to fully establish IGW tests in clinical settings.
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