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Inflammatory pseudotumor presenting as a facial swelling.
Emil Dediol1, Spomenka Manojlović, Cedna Tomasović Loncarić
1University of Zagreb, Dubrava University Hospital, Department of Maxillofacial Surgery, Zagreb, Croatia. emildediol@yahoo.com
Collegium Antropologicum
|February 13, 2013
Summary
This case study highlights inflammatory pseudotumor (IPT) presenting as facial swelling. Diagnosis required excluding other conditions, emphasizing IPT as a rare differential for facial masses.
Area of Science:
- Pathology
- Oncology
- Maxillofacial Surgery
Background:
- Inflammatory pseudotumor (IPT) is a rare benign lesion.
- Facial swelling can have diverse etiologies, including infection and malignancy.
- Accurate diagnosis of facial masses is crucial for appropriate management.
Observation:
- A patient presented with persistent facial swelling after trauma, initially misdiagnosed as dental infection.
- Imaging revealed a mass in the infraorbital region; initial biopsy suggested lymphoma, but further analysis confirmed IPT.
- This case represents a unique presentation of head and neck IPT in the infraorbital region.
Findings:
- Pathohistological review and immunohistochemistry were crucial for establishing the IPT diagnosis by exclusion.
- The lesion showed diffuse infiltration of lymphocytes, perineural and perivascular spread, without germinative centers.
- Exclusion of B-cell lymphoma was based on PCR results indicating B-cell policlonality.
Implications:
- Accurate diagnosis of IPT is challenging due to a lack of clear histological criteria and its rarity.
- Awareness of IPT is essential for clinicians managing facial swelling, especially after trauma.
- This case expands the known anatomical locations for head and neck IPT.
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