Related Experiment Video
Updated: Aug 12, 2026

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders
Published on: August 18, 2023
Cor pulmonale: correlation with central airway lesions, peripheral airway lesions, emphysema, and control of
K Jamal1, J A Fleetham, W M Thurlbeck
1Department of Medicine, University Hospital, Vancouver, British Columbia.
Abstract:
We have analyzed the heart and lung findings in 31 patients in the National Institutes of Health (NIH) Nocturnal Oxygen Therapy Trial (NOTT) with particular emphasis on cor pulmonale. Increased right ventricular weight was related to decreased bronchiolar diameter, decreased ratio of bronchiolar diameter to external arterial diameter, and an increased proportion of airways less than 400 microns in diameter. No relationship was found between the severity of emphysema, mucous gland enlargement, peripheral airway mucous plugging, or other measurement of central and peripheral airways. Patients with right ventricles weighing more than 100 g had higher pulmonary artery pressures at rest and higher arterial CO2 levels than those weighing 100 g or less. When the patients were divided into Types A, B, and X according to Burrows' criteria, those with Type X had a higher volume proportion of mucous glands; type B were intermediate; and Type A had the smallest. The amount of bronchial muscle was less in Type B patients than in Type A, and right ventricles weighted less in Type A patients than in Type B. Hypoxic ventilatory drive was lower in Type B patients than in Type A. Absolute right ventricular weight appeared to be a better measurement of right ventricular enlargement than relative right ventricular weight in the NIH NOTT patients. We conclude that right ventricular weight in patients with hypoxic chronic airflow obstruction (CAO) is related to airway narrowing, and that the Type B syndrome is associated with decreased ventilatory drive.
More Related Videos
02:09Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Published on: April 12, 2024
04:53Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Published on: October 18, 2024
Related Concept Videos
Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Chronic Obstructive Pulmonary Disease II: Emphysema
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations