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Published on: October 31, 2019
Pediatric anophthalmic sockets and orbital implants: outcomes with polymer-coated implants
Maria Kirzhner1, Yevgeniy Shildkrot, Barrett G Haik
1Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.
Purpose:
To compare wrapped and polymer-coated hydroxyapatite implants in children undergoing primary enucleation with no adjuvant therapies.
Design:
Retrospective, interventional cohort study.
Participants:
All children undergoing primary enucleation without adjuvant therapies between 1999 and 2009 at a tertiary pediatric cancer hospital.
Methods:
Review and analysis of patient records.
Main Outcome Measures:
Implant exposure, extrusion and migration, socket contracture, and formation of pyogenic granuloma.
Results:
Sixty consecutive patients undergoing primary enucleation with no adjuvant chemotherapy or radiation with follow-up of at least 12 months were included. Retinoblastoma was the diagnosis in 59 eyes (98.3%). Median follow-up was 3.6 years (range, 1.0-9.3 years). Two implant sizes were used: 20 mm in 47 patients (78.3%) and 18 mm in 13 patients (21.7%). Overall, 52 patients (86.7%) had an event-free recovery. Polymer-coated hydroxyapatite implants (43/60, 71.7%), when compared with wrapped ones (17/60, 28.3%), had a trend toward greater event-free recovery (odds ratio [OR], 1.6; 95% confidence interval [CI], 0.3-7.7) and lower exposure rate (OR, 2.1; 95% CI, 0.4-10.5).
Conclusions:
The use of polymer-coated hydroxyapatite implants is associated with favorable outcomes in the pediatric population. Despite observed complications, long-term implant retention is possible in most children.
Financial Disclosure(S):
The author(s) have no proprietary or commercial interest in any materials discussed in this article.
