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Related Concept Videos

Gallbladder01:17

Gallbladder

The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins the common...
Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Scanning Electron Microscopy01:07

Scanning Electron Microscopy

A scanning electron microscope (SEM) is used to study the surface features of a sample by using an electron beam that scans the sample surface in a two-dimensional manner. Typically, areas between ~1 centimeter to 5 micrometers in width can be imaged. SEM can be used to image bacteria, viruses, tissues as well as larger samples like insects. Conventional SEM gives a magnification ranging from 20X to 30,000X and spatial resolution of 50 to 100 nanometers.
Fundamental Principles
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Related Experiment Video

Updated: May 14, 2026

A Standardized Method for the Analysis of Liver Sinusoidal Endothelial Cells and Their Fenestrations by Scanning Electron Microscopy
08:38

A Standardized Method for the Analysis of Liver Sinusoidal Endothelial Cells and Their Fenestrations by Scanning Electron Microscopy

Published on: April 30, 2015

A microstructural study of gallbladder stones using scanning electron microscopy.

Tie Qiao1, Rui-Hong Ma, Xiao-Bing Luo

  • 1Institute of Gallbladder Disease of Panyu, Nansha, Guangzhou, People's Republic of China. fqj1958@163.com

Microscopy Research and Technique
|February 13, 2013
PubMed
Summary
This summary is machine-generated.

This study reveals distinct microstructures for various gallbladder stones, offering insights into their formation. Understanding these stone types aids in further research on cholecystolithiasis.

Related Experiment Videos

Last Updated: May 14, 2026

A Standardized Method for the Analysis of Liver Sinusoidal Endothelial Cells and Their Fenestrations by Scanning Electron Microscopy
08:38

A Standardized Method for the Analysis of Liver Sinusoidal Endothelial Cells and Their Fenestrations by Scanning Electron Microscopy

Published on: April 30, 2015

Area of Science:

  • Gastroenterology and Hepatology
  • Biomineralization
  • Medical Imaging

Background:

  • Gallbladder stones (cholecystolithiasis) are common, but their formation mechanisms require further elucidation.
  • Understanding the microstructure of different gallstone types is crucial for comprehending their pathogenesis.

Purpose of the Study:

  • To characterize the microstructural features of diverse gallbladder stone compositions.
  • To establish a basis for understanding gallstone formation through detailed morphological analysis.

Main Methods:

  • Fourier Transform Infrared spectroscopy (FTIR) was employed for initial gallstone typing.
  • Scanning Electron Microscopy (SEM) was utilized to examine the microstructural characteristics of 387 patient gallstones.

Main Results:

  • Cholesterol stones exhibit lamellar crystals; pigment stones show loosely arranged bilirubinate particles.
  • Calcium carbonate stones display diverse crystal morphologies, with bulbiform shapes being most frequent.
  • Phosphate, calcium stearate, protein, and cystine stones present unique structures, while mixed stones vary based on components.

Conclusions:

  • Each gallbladder stone type possesses characteristic microstructural elements and morphologies.
  • This detailed microstructural analysis provides an objective foundation for future research into gallstone formation and prevention.