Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

DNA Agarose Gel Electrophoresis02:35

DNA Agarose Gel Electrophoresis

Agarose gel electrophoresis is a laboratory technique commonly used to separate DNA fragments by size. However, it can also be used to isolate and purify DNA fragments using a gel extraction protocol.
Gel extraction follows five major steps: running gel electrophoresis to separate fragments, isolating the individual bands, extracting DNA from those bands, and removing the dye and salts from the extracted mixture to obtain pure DNA.
In cloning experiments, both the insert and vector DNA...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Spatially Resolved Diffusion NMR for Structurally Heterogeneous Materials.

Analytical chemistry·2026
Same author

Lithium-selective supramolecular assembly and capture by tripeptide gelators.

Chemical science·2026
Same author

Safety-focused development and evaluation of an LLM sexual well-being chatbot for women: A methods-focused feasibility study.

Digital health·2026
Same author

Structural basis of supercoiling-induced CRISPR-Cas9 off-target activity.

Nature·2026
Same author

Chart builder: an interactive tool for user driven data visualization in the electron microscopy data bank.

Frontiers in bioinformatics·2026
Same author

MolViewStories: Interactive molecular storytelling.

Protein science : a publication of the Protein Society·2026

Related Experiment Video

Updated: May 14, 2026

Thermal Scanning Conductometry (TSC) as a General Method for Studying and Controlling the Phase Behavior of Conductive Physical Gels
10:01

Thermal Scanning Conductometry (TSC) as a General Method for Studying and Controlling the Phase Behavior of Conductive Physical Gels

Published on: January 23, 2018

Chemically programmed self-sorting of gelator networks.

Kyle L Morris1, Lin Chen, Jaclyn Raeburn

  • 1School of Life Sciences, Chichester II Building, University of Sussex, Falmer BN1 9QG, UK.

Nature Communications
|February 14, 2013
PubMed
Summary
This summary is machine-generated.

Researchers developed a pH-controlled method for self-sorting molecules in water, enabling precise control over the formation of complex supramolecular materials. This breakthrough allows for the preprogramming of assembly order, advancing functional material design.

More Related Videos

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks
07:50

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

Published on: November 25, 2015

Related Experiment Videos

Last Updated: May 14, 2026

Thermal Scanning Conductometry (TSC) as a General Method for Studying and Controlling the Phase Behavior of Conductive Physical Gels
10:01

Thermal Scanning Conductometry (TSC) as a General Method for Studying and Controlling the Phase Behavior of Conductive Physical Gels

Published on: January 23, 2018

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
12:07

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning

Published on: April 16, 2018

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks
07:50

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

Published on: November 25, 2015

Area of Science:

  • Supramolecular chemistry
  • Materials science
  • Chemical engineering

Background:

  • Controlling multicomponent self-assembly for functional materials is challenging.
  • Molecules in solution can coassemble or self-sort into homomolecular assemblies.
  • One-pot fabrication of separate, ordered assemblies from complex mixtures is difficult.

Purpose of the Study:

  • To report the first example of pH-controlled self-sorting of gelators in water.
  • To demonstrate a method for predefining the order of supramolecular assembly.
  • To enable the formation of complex structures not achievable by simple thermal gelation.

Main Methods:

  • Utilized pH control to direct the self-sorting of different gelator molecules.
  • Leveraged the pKa of gelators to preprogram their assembly behavior.
  • Investigated self-assembly in aqueous solutions.

Main Results:

  • Achieved the first demonstration of pH-controlled self-sorting of gelators in water.
  • Successfully preprogrammed the order of molecular assembly.
  • Formed distinct, self-assembled networks from a mixture of components.

Conclusions:

  • pH-programming offers a novel strategy for controlling supramolecular self-assembly.
  • This method allows for the creation of complex, ordered materials from multicomponent systems.
  • The approach advances the design of functional supramolecular materials.