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Published on: January 7, 2018
Longitudinal study shows increasing obesity and hyperglycemia in micronesia
David Murdock1, Jacqueline Salit, Markus Stoffel
1Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.
Obesity and hyperglycemia rates dramatically increased in Kosrae, highlighting urgent public health concerns. This study documents significant metabolic health declines in the indigenous population over a seven-year period.
Area of Science:
- Metabolic health
- Epidemiology
- Indigenous health
Background:
- Indigenous populations exposed to Western lifestyles face high rates of obesity and diabetes.
- The Micronesian island of Kosrae is experiencing significant health challenges.
Purpose of the Study:
- To describe the prevalence of obesity, diabetes, hyperglycemia, dyslipidemia, and hypertension in Kosrae.
- To assess changes in these metabolic traits over time.
Main Methods:
- Longitudinal metabolic screenings of adult Kosraens (age ≥ 20) in 1994 and 2001.
- Inclusion of approximately 80% of the adult population (3,106 individuals).
- Diagnosis of diabetes using World Health Organization guidelines; assessment of obesity, hyperglycemia, dyslipidemia, and hypertension.
Main Results:
- Age-adjusted diabetes prevalence rose from 14% to 21%.
- Significant increases in obesity (45% to 62%) and hyperglycemia (19% to 44%), particularly among young Kosraens and women.
- High prevalence of low high-density lipoprotein (HDL) (80%), with relatively normal triglyceride levels.
Conclusions:
- A dramatic increase in obesity and hyperglycemia observed in Kosrae within a 7-year period.
- These findings indicate substantially increased future health risks for the region.
- Urgent public health interventions are needed to address the escalating metabolic disease burden.
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