Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 14, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Refractory migraine - a review.

Elliott Schulman1

  • 1Lankenau Medical Center and Lankenau Institute for Medical Research, Wynnewood, PA, USA.

Headache
|February 15, 2013
PubMed
Summary
This summary is machine-generated.

Refractory migraine, a challenging condition for headache specialists, significantly impairs quality of life. This review explores its definitions, epidemiology, pathophysiology, and various treatment strategies for better patient outcomes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Current concepts in refractory migraine.

Current treatment options in neurology·2012
Same author

Adverse childhood experiences and frequent headaches in adults.

Headache·2010
See all related articles

Area of Science:

  • Neurology
  • Headache Medicine

Background:

  • Refractory migraine presents a significant clinical challenge, affecting patients despite optimal treatment.
  • This patient subgroup experiences substantial disability and reduced quality of life.

Purpose of the Study:

  • To review proposed definitions and epidemiology of refractory migraine.
  • To explore the pathophysiology underlying this disorder.
  • To summarize current and potential treatment modalities.

Main Methods:

  • Literature review of proposed definitions and epidemiological data.
  • Analysis of pathophysiological mechanisms contributing to refractory migraine.
  • Review of pharmacological, complementary, and invasive treatment options.

More Related Videos

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies
05:49

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies

Published on: November 1, 2024

Investigating Migraine-Like Behavior Using Light Aversion in Mice
05:23

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

Related Experiment Videos

Last Updated: May 14, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies
05:49

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies

Published on: November 1, 2024

Investigating Migraine-Like Behavior Using Light Aversion in Mice
05:23

Investigating Migraine-Like Behavior Using Light Aversion in Mice

Published on: August 11, 2021

Main Results:

  • Discussion of various proposed definitions and epidemiological findings.
  • Exploration of potential pathophysiological contributors.
  • Overview of treatment strategies, including medication, adjunct therapies, and invasive procedures.

Conclusions:

  • Refractory migraine requires a comprehensive understanding of its multifaceted nature.
  • Optimal management involves addressing comorbid factors, medication overuse, and treatment pitfalls.
  • Further research is crucial to improve therapeutic outcomes for these patients.