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Age-related changes in hyaluronate uptake by cultured fibroblasts
R Evangelisti1, G Stabellini, P Carinci
1Institute of Histology and General Embryology, University of Ferrara, Italy.
Cell Biochemistry and Function
|January 1, 1990
Abstract:
Skin fibroblasts from chick embryos of 7 and 14 days incubation have been tested for their ability to bind, internalize and degrade [3H]-hyaluronan. Seven-day fibroblasts internalize and degrade a greater amount of labelled hyaluronan than 14-day cells. The implications of these findings in the regulation by the fibroblasts of extracellular matrix composition in glycosaminoglycans are discussed.