Related Experiment Video
Updated: May 14, 2026
Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
Published on: September 22, 2023
Adenoidal hypertrophy and allergic rhinitis: is there an inverse relationship?
Franco Ameli1, Fabio Brocchetti, Maria Angela Tosca
1Ear, Nose, and Throat Unit, Villa Montallegro Private Clinic, Genoa, Italy.
Background:
Nasal obstruction is a very common symptom in children. The main causes are allergic rhinitis (AR) and adenoidal hypertrophy (AH); the possible correlation between AR and AH has been investigated by few studies, mainly conducted using radiographic craniometry. This study aimed at investigating this topic by nasal endoscopy.
Methods:
There were 205 children (134 boys; mean age, 6.7 years age range, 4-12 years) studied. Clinical visit, nasal endoscopy, and skin-prick test were performed in all patients. Anterior nasal obstruction was graded using the Friedmann's classification. Adenoid size was graded using the Parikh's classification. Perception of symptoms by children was also assessed using the visual analog scale.
Results:
Ninety-two children (44.9%) had complete nasal obstruction and 28 children (13.7%) had choanae invasion. There was a negative significant correlation (r = -0.41; p < 0.001) between nose obstruction severity and volume of adenoids. Decreased probability of greater adenoid volume was associated with increased severity of nose obstruction (odds ratio [OR] = 0.13) and in patients with allergy compared with nonallergic patients (OR = 0.31).
Conclusion:
This real-life study shows that large adenoids may be associated with absence of allergy, whereas large turbinates may be associated with small adenoids.
Related Concept Videos
01:28Asthma I: Introduction
01:16Drugs Used in Upper Respiratory Disorders: Overview
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
01:26Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
01:23Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
01:27Upper Respiratory Drugs: Decongestants
Most decongestants are readily available over-the-counter in various...
01:20Asthma: Pathogenesis and Management
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.