Related Experiment Video
Updated: May 14, 2026

Clinical Assessment of Spatiotemporal Gait Parameters in Patients and Older Adults
Published on: November 7, 2014
[High blood pressure and mortality in the elderly: what does gait speed tell?]
Majon Muller1, Andrea B Maier, Yvo M Smulders
1VU medisch centrum, afd. Interne Geneeskunde, Amsterdam. m.muller@vumc.nl
Insights
High blood pressure in older adults needs personalized treatment. Gait speed can help tailor treatments for elderly individuals to reduce mortality risk.
Area of Science:
- Gerontology
- Cardiovascular Medicine
- Public Health
Context:
- Evidence on high blood pressure (hypertension) primarily focuses on middle-aged populations.
- The predictive value and treatment efficacy of hypertension in the elderly remain unclear.
- Current 'lower is better' guidelines may not be universally applicable to all older adults.
Purpose:
- To investigate the predictive value of hypertension in the elderly.
- To determine if hypertension treatment in older adults reduces mortality risk.
- To explore the utility of gait speed as a proxy for biological age in hypertension management.
Summary:
- Gait speed, a measure of frailty, can serve as a biological age indicator.
- This approach can help understand the relationship between late-life blood pressure and mortality.
- It aids in identifying elderly individuals who would benefit most from antihypertensive therapy.
Impact:
- Highlights the need for age-specific hypertension guidelines for the elderly.
- Promotes a shift from chronological to biological age in clinical decision-making.
- Facilitates personalized blood pressure management for the aging hypertensive population.
Abstract:
Despite the large body of evidence available for the middle-aged population, it is still unclear what the predictive value of high blood pressure in the elderly population is, or whether it should be treated to reduce the risk of mortality. Since the current guideline proposing that 'lower is better' may not apply to the blood pressure levels of all elderly and the management thereof, specific guidelines that are dependent on the biological age of older persons are needed. Gait speed, as a proxy for frailty or biological age, could be utilised as a foundation for understanding the complex relationship between late-life blood pressure levels and mortality risk, and for categorising those older persons who are most likely to benefit from antihypertensive treatment. Increasing general awareness about the option of categorising individuals based on their biological age instead of chronological age will help to facilitate tailor-made blood pressure treatment for the aging hypertensive population.
Related Concept Videos
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion
Pharmacodynamics in Geriatric Patients: Effects of Age
Hypertension II: Pathophysiology
Assessing Blood pressure in the Leg
Preparation:
Drug Dosing: Geriatric Patients
Pre-Procedural Guidelines for Assessing Blood Pressure

