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Updated: May 14, 2026

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In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
[Progress in the pathologic study of small renal masses. Can diagnostic accuracy be improved?]
1Sección de Patología, Fundació Puigvert, Universidad Autónoma de Barcelona, Barcelona, España. falgaba@fundacio-puigvert.es
Archivos Espanoles De Urologia
|February 15, 2013
Summary
Pathology, specifically biopsy, is crucial for determining the biology of small renal masses (SRMs). This aids in making informed therapeutic decisions for these tumors.
Area of Science:
- Uropathology
- Oncology
- Diagnostic Pathology
Context:
- Increasing diagnosis of small renal masses (SRMs) ≤ 4 cm due to early detection.
- Need to understand the biology of SRMs to guide treatment.
- Pathology plays a key role in characterizing renal masses.
Purpose:
- To review the utility of pathology in determining the biology of small renal masses.
- To detail how pathological methods can aid in the diagnosis and management of SRMs.
Summary:
- Renal mass size on CT correlates with specimen measurements.
- Biopsy is the primary method for determining SRM biology, achieving high rates for histologic subtype and grade determination.
- Combining biopsy with FNAC, immunohistochemistry, FISH, and molecular methods can further enhance diagnostic accuracy.
Impact:
- Pathological evaluation of SRMs provides essential data for therapeutic indications.
- Biopsy findings help differentiate tumor types and aggressiveness.
- Supports personalized treatment strategies for small renal masses.
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