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Updated: May 14, 2026

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DNAzyme 10-23 - Based Nanomachines for Nucleic Acid Recognition
Published on: February 9, 2024
Direct detection of unamplified genomic DNA based on photo-induced silver ion reduction by DNA molecules
Ye Lim Jung1, Cheulhee Jung, Jung Hun Park
1Department of Chemical and Biomolecular Engineering (BK 21 program), Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 305-701, Republic of Korea.
Abstract:
A label-free, colorimetric method has been developed for ultrasensitive detection of nucleic acids that is based on photoinduced silver ion (Ag(+)) reduction around DNA bases. The assay system is capable of directly detecting bacterial genomic DNA without the need for PCR amplification.
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