Related Experiment Video
Updated: May 14, 2026

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021
Vitreous hemorrhage in children and adolescents in India
Pukhraj Rishi1, Ekta Rishi, Aditi Gupta
1Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralya, Tamil Nadu, India. docrishi@yahoo.co.in
Insights
Vitreous hemorrhage in children is most often caused by trauma, particularly blunt injuries. Factors like male sex, older age, unilateral presentation, and surgery correlate with severe vision loss in pediatric patients.
Area of Science:
- Ophthalmology
- Pediatric Medicine
- Trauma Research
Background:
- Vitreous hemorrhage in pediatric patients is a significant cause of vision impairment.
- Understanding the etiologies and outcomes is crucial for effective management in young individuals.
Purpose of the Study:
- To detail the clinical characteristics, causes, treatments, and outcomes of vitreous hemorrhage in patients under 18 in India.
- To identify risk factors associated with severe visual loss in this demographic.
Main Methods:
- Retrospective review of medical records for patients with vitreous hemorrhage from January 2000 to January 2010.
- Analysis of 261 eyes from 246 pediatric patients, categorizing causes, treatments, and visual outcomes.
Main Results:
- Trauma accounted for 68.5% of vitreous hemorrhage cases, with blunt trauma being more prevalent than penetrating trauma.
- Spontaneous causes included Eales disease and retinopathy of prematurity sequelae.
- Male sex, age over 8 years, unilateral presentation, and surgical intervention were linked to severe visual loss.
Conclusions:
- Posttraumatic vitreous hemorrhage is the predominant cause in children and adolescents, with blunt trauma being more frequent.
- Risk factors for severe vision loss in pediatric vitreous hemorrhage include male gender, older age, unilateral presentation, and surgical treatment.
Purpose:
To report the clinical profile, etiologies, treatment modalities, and outcomes for vitreous hemorrhage in patients <18 years of age in India.
Methods:
The medical records of patients presenting with vitreous hemorrhage between January 2000 and January 2010 were retrospectively reviewed.
Results:
A total of 261 eyes of 246 patients (201 males) were included. Of these patients, 231 (94%) were unilateral. Trauma was the leading cause of injury in 179 eyes (68.5%); blunt trauma was more common than penetrating trauma in both males (64.7%) and females (57.7%). Wooden sticks were the most common cause of trauma (20.7%). Spontaneous causes accounted for 82 (31.5%) eyes, including 33 eyes (40%) with Eales disease, and 16 eyes (19.7%) with sequelae of retinopathy of prematurity. Trauma was most common cause of vitreous hemorrhage in all age groups, except in children <4 years of age, in whom spontaneous hemorrhage predominated. Overall, the most common management was surgery, performed in 173 (66.2%) eyes; 63 (24.1%) eyes were observed. Male sex, age >8 years, unilateral presentation, surgical treatment (P < 0.001), and blunt trauma (P = 0.047) were associated with severe visual loss. Mean follow-up was 636.5 ± 802.0 days overall, 597.0 ± 749.0 days for eyes observed and 638.8 ± 802.6 days for eyes that underwent surgery.
Conclusions:
Posttraumatic vitreous hemorrhage comprises almost two-thirds of children and adolescents presenting with vitreous hemorrhage. Blunt trauma is more common than penetrating trauma. Male sex, age >8 years, unilateral presentation, and surgical treatment were all significantly associated with severe visual loss.
Related Concept Videos
Diabetic Retinopathy
Glaucoma: Overview
Hemorrhagic Stroke l: Introduction
Photoreceptors and Visual Pathways
Hemorrhagic Stroke ll: Pathophysiology
